| Players Picked at #166 | ||||||||||
| Season | Pick # | Team | Name | Position | College | |||||
| 2025 | 166 | Seattle Seahawks | Tory Horton | WR | Colorado State | |||||
| 2024 | 166 | New York Giants | Tyrone Tracy Jr. | RB | Purdue | |||||
| 2023 | 166 | Kansas City Chiefs | B.J. Thompson | LB | Stephen F. Austin | |||||
| 2022 | 166 | Cincinnati Bengals | Tycen Anderson | S | Toledo | |||||
| 2021 | 166 | Carolina Panthers | Keith Taylor | CB | Washington | |||||
| 2020 | 166 | Detroit Lions | Quintez Cephus | WR | Wisconsin | |||||
| 2019 | 166 | Los Angeles Chargers | Easton Stick | QB | North Dakota State | |||||
| 2018 | 166 | Buffalo Bills | Wyatt Teller | G | Virginia Tech | |||||
| 2017 | 166 | Philadelphia Eagles | Shelton Gibson | WR | West Virginia | |||||
| 2016 | 166 | Houston Texans | D.J. Reader | DT | Clemson | |||||
| 2015 | 166 | New England Patriots | Joe Cardona | LS | Navy | |||||
| 2014 | 166 | Indianapolis Colts | Jonathan Newsome | DE | Ball State | |||||
| 2013 | 166 | Miami Dolphins | Caleb Sturgis | K | Florida | |||||
| 2012 | 166 | Cincinnati Bengals | Marvin Jones | WR | California | |||||
| 2011 | 166 | Carolina Panthers | Lawrence Wilson | LB | Connecticut | |||||
| 2010 | 166 | Pittsburgh Steelers | Stevenson Sylvester | LB | Utah | |||||
| 2009 | 166 | Dallas Cowboys | Michael Hamlin | S | Clemson | |||||
| 2008 | 166 | San Diego Chargers | Marcus Thomas | RB | UTEP | |||||
| 2007 | 166 | Jacksonville Jaguars | Derek Landri | DT | Notre Dame | |||||
| 2006 | 166 | Baltimore Ravens | Quinn Sypniewski | TE | Colorado | |||||
| 2005 | 166 | Pittsburgh Steelers | Rian Wallace | LB | Temple | |||||
| 2004 | 166 | Oakland Raiders | Shawn Johnson | DE | Delaware | |||||
| 2003 | 166 | Green Bay Packers | Hunter Hillenmeyer | OLB | Vanderbilt | |||||
| 2002 | 166 | Pittsburgh Steelers | Verron Haynes | RB | Georgia | |||||
| 2001 | 166 | Arizona Cardinals | Bobby Newcombe | WR | Nebraska | |||||
| 2000 | 166 | New Orleans Saints | Chad Morton | KR | USC | |||||
| 1999 | 166 | Pittsburgh Steelers | Malcolm Johnson | WR | Notre Dame | |||||
| 1998 | 166 | Atlanta Falcons | Elijah Williams | CB | Florida | |||||
| 1997 | 166 | Miami Dolphins | John Fiala | LB | Washington | |||||
| 1996 | 166 | Oakland Raiders | La'Roi Glover | DT | San Diego State | |||||
| 1995 | 166 | Dallas Cowboys | Ed Hervey | WR | USC | |||||
| 1994 | 166 | New England Patriots | Steve Hawkins | WR | Western Michigan | |||||
| 1993 | 166 | San Francisco 49ers | Chris Dalman | G | Stanford | |||||
| 1992 | 166 | New York Jets | Jeff Blake | QB | East Carolina | |||||
| 1991 | 166 | Buffalo Bills | Millard Hamilton | WR | Clark | |||||
| 1990 | 166 | Buffalo Bills | Brent Griffith | G | Minnesota-Duluth | |||||
| 1989 | 166 | Cincinnati Bengals | Craig Taylor | RB | West Virginia | |||||
| 1988 | 166 | Atlanta Falcons | Michael Haynes | WR | Northern Arizona | |||||
| 1987 | 166 | Los Angeles Rams | Jon Embree | TE | Colorado | |||||
| 1986 | 166 | Chicago Bears | Jeff Powell | RB | Tennessee | |||||
| 1985 | 166 | New York Jets | Rich Miano | DB | Hawaii | |||||
| 1984 | 166 | Dallas Cowboys | Joe Levelis | G | Iowa | |||||
| 1983 | 166 | Washington Redskins | Bob Winckler | T | Wisconsin | |||||
| 1982 | 166 | Cincinnati Bengals | Arthur King | DE | Grambling State | |||||
| 1981 | 166 | New Orleans Saints | Glen Redd | LB | BYU | |||||
| 1980 | 166 | Detroit Lions | Eddie Murray | K | Tulane | |||||
| 1979 | 166 | San Francisco 49ers | Phil Francis | RB | Stanford | |||||
| 1978 | 166 | Dallas Cowboys | Harold Randolph | LB | East Carolina | |||||
| 1977 | 166 | Detroit Lions | Reggie Pinkney | DB | East Carolina | |||||
| 1976 | 166 | Kansas City Chiefs | Steve Taylor | DB | Kansas | |||||
| 1975 | 166 | Buffalo Bills | Gil Chapman | RB | Michigan | |||||
| 1974 | 166 | San Francisco 49ers | Kermit Johnson | RB | UCLA | |||||
| 1973 | 166 | Denver Broncos | John Grant | DE | USC | |||||
| 1972 | 166 | New England Patriots | John Tarver | RB | Colorado | |||||
| 1971 | 166 | Washington Redskins | Willie Germany | DB | Morgan State | |||||
| 1970 | 166 | New Orleans Saints | Lon Woodard | DE | San Diego State | |||||
| 1969 | 166 | Washington Redskins | Jeff Anderson | RB | Virginia | |||||
| 1968 | 166 | Cincinnati Bengals | Steve Smith | TE | Miami (FL) | |||||
| 1967 | 166 | Detroit Lions | Ted Tuinstra | T | Iowa State | |||||
| 1966 | 166 | San Francisco 49ers | Preston Ridlehuber | RB | Georgia | |||||
| 1965 | 166 | St. Louis Cardinals | Glen Sasser | E | North Carolina State | |||||
| 1964 | 166 | Cleveland Browns | Ed Mitchell | T | Southern | |||||
| 1963 | 166 | New York Giants | Ed Adamchik | G | Pittsburgh | |||||
| 1962 | 166 | New York Giants | Al Gursky | RB | Penn State | |||||
| 1961 | 166 | Green Bay Packers | John Denvir | G | Colorado | |||||
| 1960 | 166 | San Francisco 49ers | Gary Campbell | B | Whittier | |||||
| 1959 | 166 | New York Giants | Roger Ellis | C | Maine | |||||
| 1958 | 166 | New York Giants | C.R. Roberts | B | USC | |||||
| 1957 | 166 | Chicago Cardinals | Bob Fee | B | Indiana | |||||
| 1956 | 166 | Washington Redskins | Pat Uebel | B | Army | |||||
| 1955 | 166 | Philadelphia Eagles | Tommy Bell | B | Army | |||||
| 1954 | 166 | Los Angeles Rams | Mitchell Johnson | B | Bishop | |||||
| 1953 | 166 | New York Giants | J.L. Hall | B | Florida | |||||
| 1952 | 166 | San Francisco 49ers | Frank Simons | E | Nebraska | |||||
| 1951 | 166 | Philadelphia Eagles | Bobby Walston | E | Georgia | |||||
| 1950 | 166 | Chicago Bears | Frank Dempsey | T | Florida | |||||
| 1949 | 166 | New York Giants | Wally Teninga | B | Michigan | |||||
| 1948 | 166 | New York Giants | Don Ettinger | G | Kansas | |||||
| 1947 | 166 | Detroit Lions | Buryl Baty | B | Texas A&M | |||||
| 1946 | 166 | Green Bay Packers | Boyd Morse | E | Arizona | |||||
| 1945 | 166 | Brooklyn Tigers | Arnie Weinmeister | DT | Washington | HOF - 1984 | ||||
| 1944 | 166 | Brooklyn Tigers | Howard Maley | B | SMU | |||||
| 1943 | 166 | New York Giants | Dwight Holshouser | B | Catawba | |||||
| 1942 | 166 | Washington Redskins | Gene Stewart | B | Willamette | |||||
| 1941 | 166 | Green Bay Packers | Heige Pukema | G | Minnesota | |||||
| 1940 | 166 | Detroit Lions | Frank Ribar | G | Duke | |||||
| 1939 | 166 | Chicago Bears | Solly Sherman | B | Chicago | |||||
