| Players Picked at #110 | ||||||||||
| Season | Pick # | Team | Name | Position | College | |||||
| 2025 | 110 | New York Jets | Arian Smith | WR | Georgia | |||||
| 2024 | 110 | New England Patriots | Javon Baker | WR | Central Florida | |||||
| 2023 | 110 | Indianapolis Colts | Adetomiwa Adebawore | DE | Northwestern | |||||
| 2022 | 110 | Baltimore Ravens | Daniel Faalele | T | Minnesota | |||||
| 2021 | 110 | Cleveland Browns | James Hudson | T | Cincinnati | |||||
| 2020 | 110 | New York Giants | Darnay Holmes | CB | UCLA | |||||
| 2019 | 110 | Cincinnati Bengals | Mitch Wishnowsky | P | Utah | |||||
| 2018 | 110 | Oakland Raiders | Nick Nelson | CB | Wisconsin | |||||
| 2017 | 110 | Jacksonville Jaguars | Dede Westbrook | WR | Oklahoma | |||||
| 2016 | 110 | Los Angeles Rams | Tyler Higbee | TE | Western Kentucky | |||||
| 2015 | 110 | Minnesota Vikings | T.J. Clemmings | T | Pittsburgh | |||||
| 2014 | 110 | St Louis Rams | Maurice Alexander | S | Utah State | |||||
| 2013 | 110 | New York Giants | Ryan Nassib | QB | Syracuse | |||||
| 2012 | 110 | San Diego Chargers | Ladarius Green | TE | Louisiana-Lafayette | |||||
| 2011 | 110 | Dallas Cowboys | David Arkin | G | Missouri State | |||||
| 2010 | 110 | San Diego Chargers | Darrell Stuckey | S | Kansas | |||||
| 2009 | 110 | Dallas Cowboys | Victor Butler | DE | Oregon State | |||||
| 2008 | 110 | Miami Dolphins | Shawn Murphy | T | Utah State | |||||
| 2007 | 110 | Oakland Raiders | John Bowie | CB | Cincinnati | |||||
| 2006 | 110 | Cleveland Browns | Leon Williams | LB | Miami (FL) | |||||
| 2005 | 110 | New York Giants | Brandon Jacobs | RB | Southern Illinois | |||||
| 2004 | 110 | Chicago Bears | Nathan Vasher | CB | Texas | |||||
| 2003 | 110 | Seattle Seahawks | Seneca Wallace | QB | Iowa State | |||||
| 2002 | 110 | Tennessee Titans | Mike Echols | CB | Wisconsin | |||||
| 2001 | 110 | Buffalo Bills | Brandon Spoon | ILB | North Carolina | |||||
| 2000 | 110 | Cleveland Browns | Aaron Shea | TE | Michigan | |||||
| 1999 | 110 | San Francisco 49ers | Pierson Prioleau | S | Virginia Tech | |||||
| 1998 | 110 | Minnesota Vikings | Kivuusama Mays | LB | North Carolina | |||||
| 1997 | 110 | Kansas City Chiefs | Pat Barnes | QB | California | |||||
| 1996 | 110 | Jacksonville Jaguars | Reggie Barlow | WR | Alabama State | |||||
| 1995 | 110 | Dallas Cowboys | Eric Bjornson | WR | Washington | |||||
| 1994 | 110 | Seattle Seahawks | Larry Whigham | S | Louisiana-Monroe | |||||
| 1993 | 110 | New England Patriots | Corwin Brown | S | Michigan | |||||
| 1992 | 110 | Denver Broncos | Chuck Johnson | G | Texas | |||||
| 1991 | 110 | Dallas Cowboys | Kevin Harris | DE | Texas Southern | |||||
| 1990 | 110 | New England Patriots | Junior Robinson | CB | East Carolina | |||||
| 1989 | 110 | Washington Redskins | Erik Affholter | WR | USC | |||||
| 1988 | 110 | Atlanta Falcons | Charles Dimry | CB | UNLV | |||||
| 1987 | 110 | Los Angeles Raiders | Steve Beuerlein | QB | Notre Dame | |||||
| 1986 | 110 | Chicago Bears | Paul Blair | T | Oklahoma State | |||||
| 1985 | 110 | Denver Broncos | Keli McGregor | TE | Colorado State | |||||
| 1984 | 110 | Dallas Cowboys | Steve DeOssie | LB | Boston College | |||||
| 1983 | 110 | Los Angeles Raiders | Greg Townsend | DE | TCU | |||||
| 1982 | 110 | Cincinnati Bengals | Rodney Tate | RB | Texas | |||||
| 1981 | 110 | Philadelphia Eagles | Calvin Murray | RB | Ohio State | |||||
| 1980 | 110 | Pittsburgh Steelers | Bill Hurley | DB | Syracuse | |||||
| 1979 | 110 | Pittsburgh Steelers | Calvin Sweeney | WR | USC | |||||
| 1978 | 110 | Dallas Cowboys | Alois Blackwell | RB | Houston | |||||
| 1977 | 110 | Cleveland Browns | Robert Sims | DT | South Carolina State | |||||
| 1976 | 110 | Oakland Raiders | Herb McMath | LB | Morningside | |||||
| 1975 | 110 | Chicago Bears | Revie Sorey | G | Illinois | |||||
| 1974 | 110 | New York Jets | Gary Baccus | LB | Oklahoma | |||||
| 1973 | 110 | Buffalo Bills | Wallace Francis | WR | Arkansas State | |||||
| 1972 | 110 | St. Louis Cardinals | Conrad Dobler | G | Wyoming | |||||
| 1971 | 110 | Cincinnati Bengals | Arthur May | DE | Tuskegee | |||||
| 1970 | 110 | Houston Oilers | Ron Saul | G | Michigan State | |||||
| 1969 | 110 | Boston Patriots | Onree Jackson | QB | Alabama A&M | |||||
| 1968 | 110 | Oakland Raiders | Charlie Smith | RB | Utah | |||||
| 1967 | 110 | Denver Broncos | Fran Lynch | RB | Hofstra | |||||
| 1966 | 110 | Baltimore Colts | Ray Perkins | WR | Alabama | |||||
| 1965 | 110 | St. Louis Cardinals | John Meyer | LB | Notre Dame | |||||
| 1964 | 110 | Cleveland Browns | Leroy Kelly | RB | Morgan State | HOF - 1994 | ||||
| 1963 | 110 | New York Giants | Dave Herman | G | Michigan State | |||||
| 1962 | 110 | Chicago Bears | Larry Onesti | C | Northwestern | |||||
| 1961 | 110 | Cleveland Browns | Fred Cox | K | Pittsburgh | |||||
| 1960 | 110 | Los Angeles Rams | Curtis McClinton | RB | Kansas | |||||
| 1959 | 110 | Philadelphia Eagles | Rollie West | B | Villanova | |||||
| 1958 | 110 | Green Bay Packers | Carl Johnson | T | Illinois | |||||
| 1957 | 110 | Philadelphia Eagles | Don Bruhns | C | Drake | |||||
| 1956 | 110 | Detroit Lions | Joe Silas | DE | South Carolina | |||||
| 1955 | 110 | Chicago Cardinals | Frank Scaffidi | T | Marquette | |||||
| 1954 | 110 | Chicago Cardinals | Tommy Lewis | B | Alabama | |||||
| 1953 | 110 | Baltimore Colts | John Cole | B | Arkansas | |||||
| 1952 | 110 | Dallas Texans | Jim Hammond | B | Wisconsin | |||||
| 1951 | 110 | Cleveland Browns | Don Shula | B | John Carroll | |||||
| 1950 | 110 | Washington Redskins | Don Winslow | T | Iowa | |||||
| 1949 | 110 | Chicago Cardinals | Stan Flowers | E | Redlands | |||||
| 1948 | 110 | Los Angeles Rams | Bob Heck | E | Purdue | |||||
| 1947 | 110 | Philadelphia Eagles | John Hamberger | T | SMU | |||||
| 1946 | 110 | Los Angeles Rams | Ted Strojny | T | Holy Cross | |||||
| 1945 | 110 | Brooklyn Tigers | John Martin | B | East Tennessee State | |||||
| 1944 | 110 | Chicago Cardinals | Leo Daniels | B | Texas A&M | |||||
| 1943 | 110 | Washington Redskins | Dan Wood | C | Mississippi | |||||
| 1942 | 110 | Chicago Bears | Jim Daniell | T | Ohio State | |||||
| 1941 | 110 | Washington Redskins | Herbert Banta | B | USC | |||||
| 1940 | 110 | New York Giants | Ed McGee | G | Temple | |||||
| 1939 | 110 | New York Giants | Bruno Schroeder | E | Texas A&M | |||||
| 1938 | 110 | Chicago Bears | Fred Dreher | E | Denver | |||||
